Anna Magdalena Ubele was born on February 24, 1668 in Gross-Aspach, Wurttemburg, Germany to Hans Johannas Ubele and Anna Magdelena Muller. She married Johann Conrad Weiser in 1686 in Gross-Aspach. They had a total of 13 children. After the land that they lived in was revaged after war, pestilence, and an unusually cold and long winter, Anna died of a fever on May 10, 1709. Her son, Johann Conrad Weiser, Jr. writes, "Buried beside Her Ancestors, she was a god-fearing woman and much loved by Her neighbors. Her motto was Jesus I live for thee, I die for thee, thine am I in life and death."
Children
| Name | Birth | Death | Joined with |
| Maria Catharina Weiser (?-1761) | |||
| Anna Margaretha Weiser (?-1748) | |||
| Anna Magdalena Weiser (?-?) | |||
| Maria Sabrina Weiser (?-?) | |||
| Georg Friederich (?-?) | |||
| Johann Conrad Weiser, Jr. (1696-1760) | |||
| Christoph Friederich (1699-?) | |||
| Anna Barbara Weiser (1700-?) | 17 October 1700 (Gross Aspach+ Germany) | 1750 (Fort Plain+ New York) | Nicholas Pickard (1701-c1750) |
| Johann Friederich Weiser (1702-1702) | |||
| Rebecca Weiser (1703-1704) | |||
| Johann Friederich Weiser (1705-1711) | |||
| Erhardt Friederich Weiser (1706-1707) | |||
| Rebecca Weiser (1706-1709) | |||