Helen Kelsall Melland was born 30 October 1854 in Rochdale, Lancashire, England, United Kingdom to Frederick Melland (1818-1911) and Ann Heap Kelsall (1823-1860) and died 11 September 1891 Lamlash, Isle of Arran, Scotland, United Kingdom of unspecified causes. She married Herbert Henry Asquith, 1st Earl of Oxford and Asquith (1852-1928) 23 August 1877 in Chorlton, Lancashire, England, United Kingdom.
Children
| Name | Birth | Death | Joined with |
| Raymond Asquith (1878-1916) | 6 November 1878 Hampstead, Middlesex, England, United Kingdom | 15 September 1916 | Katharine Frances Horner (1885-1976) |
| Herbert Asquith (1881-1947) | 11 March 1881 Hampstead, Middlesex, England, United Kingdom | 5 August 1947 Cranhill Nursing Home, Bath, Somerset, England, United Kingdom | Cynthia Mary Evelyn Charteris (1887-1960) |
| Arthur Melland Asquith (1883-1939) | 24 April 1883 Hampstead, Middlesex, England, United Kingdom | 24 August 1939 Marylebone, London, England, United Kingdom | Betty Constance Manners (1889-1962) |
| Helen Violet Asquith (1887-1969) | 15 April 1887 Hampstead, Middlesex, England, United Kingdom | 15 February 1969 Paddington, Greater London, England, United Kingdom | Maurice Bonham Carter (1880-1960) |
| Cyril Asquith (1890-1954) | 5 February 1890 | 24 August 1954 | Anne Stephanie Pollock (1896-1964) |