Four or more generations of descendants of John II of Castile (1405-1454) if they are properly linked:
1. John II of Castile (1405-1454)
- 2. Catalina of Castile (1422–1424)
- 2. Leonor of Castile (1423-1425)
- 2. Henry IV of Castile (1425-1474)
- 2. María of Castile (1428-1429)
- 2. Isabella I of Castile (1451-1504)
- 3. Isabella of Asturias (1470-1498)
- 4. Miguel da Paz, Prince of Asturias (1498-1500)
- 3. Juan, Prince of Asturias (1478-1497)
- 3. Joanna of Castile (1479-1555)
- 4. Eleonore of Castile (1498-1558)
- 5. Carlos of Portugal (1520-1521) ... (more)
- 5. Maria of Portugal (1521-1577) ... (more)
- 4. Charles V of the Holy Roman Empire (1500-1558)
- 5. Philip II of Spain (1527-1598) ... (more)
- 5. Maria of Spain (1528-1603) ... (more)
- 5. Juana of Spain (1537-1573) ... (more)
- 5. Isabel de Castilla (1518-1537) ... (more)
- 5. Margaret of Austria (1522-1586) ... (more)
- 5. John of Austria (1547-1578) ... (more)
- 4. Isabella of Austria (1501-1526)
- 5. Dorothea of Denmark (1520-1580) ... (more)
- 5. Christina of Denmark (1521-1590) ... (more)
- 4. Ferdinand I, Holy Roman Emperor (1503-1564)
- 5. Elisabeth of Austria (1526-1545) ... (more)
- 5. Maximilian II, Holy Roman Emperor (1527-1576) ... (more)
- 5. Anna of Austria (1528-1590) ... (more)
- 5. Ferdinand II. von Österreich-Tirol (1529-1595) ... (more)
- 5. Maria of Austria (1531-1581) ... (more)
- 5. Magdalene of Austria (1532-1590) ... (more)
- 5. Catharine of Austria (1533-1572) ... (more)
- 5. Eleonora of Austria (1534-1594) ... (more)
- 5. Margaret of Austria (1536-1567) ... (more)
- 5. Johann of Austria (1538-1539) ... (more)
- 5. Barbara of Austria (1539-1572) ... (more)
- 5. Karl II. Franz von Innerösterreich (1540-1590) ... (more)
- 5. Ursula of Austria (1541-1543) ... (more)
- 5. Helen of Austria (1543-1574) ... (more)
- 5. Johanna of Austria (1547-1578) ... (more)
- 4. Marie of Castile (1505-1558)
- 4. Katharina of Castile (1507-1578)
- 5. Afonso of Portugal (1526-1526) ... (more)
- 5. Maria Manuela of Portugal (1527-1545) ... (more)
- 5. Isabel of Portugal (1529-1529) ... (more)
- 5. Beatriz of Portugal (1530-1530) ... (more)
- 5. Manuel of Portugal (1531-1537) ... (more)
- 5. Filipe of Portugal (1533-1539) ... (more)
- 5. Dinis of Portugal (1535-1537) ... (more)
- 5. João of Portugal (1537-1554) ... (more)
- 5. António of Portugal (1539-1540) ... (more)
- 4. Eleonore of Castile (1498-1558)
- 3. Maria of Aragon (1482-1517)
- 4. John III of Portugal (1502-1557)
- 5. Afonso of Portugal (1526-1526) ... (more)
- 5. Maria Manuela of Portugal (1527-1545) ... (more)
- 5. Isabel of Portugal (1529-1529) ... (more)
- 5. Beatriz of Portugal (1530-1530) ... (more)
- 5. Manuel of Portugal (1531-1537) ... (more)
- 5. Filipe of Portugal (1533-1539) ... (more)
- 5. Dinis of Portugal (1535-1537) ... (more)
- 5. João of Portugal (1537-1554) ... (more)
- 5. António of Portugal (1539-1540) ... (more)
- 5. Duarte of Braga (1521-1543) ... (more)
- 4. Isabella of Portugal (1503-1539)
- 5. Philip II of Spain (1527-1598) ... (more)
- 5. Maria of Spain (1528-1603) ... (more)
- 5. Juana of Spain (1537-1573) ... (more)
- 4. Beatriz of Portugal (1504-1538)
- 5. Adrien-Jean-Amédée de Savoie (1522-1523) ... (more)
- 5. Louis de Savoie (1523-1536) ... (more)
- 5. Emmanuel-Philibert de Savoie (1528-1580) ... (more)
- 5. Catherine de Savoie (1529-1536) ... (more)
- 5. Marie de Savoie (1530-1531) ... (more)
- 5. Isabelle de Savoie (1532-1533) ... (more)
- 5. Emmanuel de Savoie (1533-c1533) ... (more)
- 5. Emmanuel de Savoie (1534-?) ... (more)
- 5. Jean-Marie de Savoie (1537-1538) ... (more)
- 4. Luís of Portugal (1506-1555)
- 4. Fernando of Guarda and Trancoso (1507-1534)
- 4. Afonso of Portugal (1509-1540)
- 4. Maria of Portugal (1513-1513)
- 4. Henry I of Portugal (1512-1580)
- 4. Duarte of Guimarães (1515-1540)
- 5. Mary of Guimarães (1538-1577) ... (more)
- 5. Catherine of Guimarães (1540-1614) ... (more)
- 5. Duarte II of Guimarães (1541-1576) ... (more)
- 4. António of Portugal (1516-1516)
- 4. John III of Portugal (1502-1557)
- 3. Catherine of Aragon (1485-1536)
- 4. Henry Tudor (1511-1511)
- 4. Mary I of England (1516-1558)
- 3. Isabella of Asturias (1470-1498)
- 2. Alfonso of Asturias (1453-1468)